Evaluation and Interpretation of Laboratory Methods Effectiveness in Blood Parameters for Diagnosis of Invasive Fungal Pulmonary Disease and Comparison of Changes in Healthy Persons

Complete blood count (CBC), important information about the volume, number of cells and components of blood cells could diagnose of many diseases provided. In patients Infected with invasive pulmonary fungal disease (IFD) some of the changes in them occurs, blood index somewhat warning and of them can be used to diagnose the treatment of disease.The study was cross-sectional. In this study, 26 patients with pulmonary IFD has had an underlying medical condition referring to Shariati Hospital in Tehran during the period a year were admitted due to respiratory failure. In the control group of 26 healthy volunteers who agreed to cooperate were studied. Blood samples to count test, RBC, WBC, hematocrit and hemoglobin was performed by the Sysmex device,then calculated and compared. The data were analyzed using the software SPSS v20.The average RBC, WBC, in patients with pulmonary IFD, respectively, 3.7, 4.4 thousand per milliliter of bloods naturally, the average of hematocrit and hemoglobin 27.8% and 10.6% was calculated. But the average index in healthy people, 4.6, 8.2 thousand per milliliter of blood naturally, 43.6% and the 14.2% were calculated. However, the interpretation of this indicator is the best sensitivity (90%) and specificity (7/85%), were calculated.The study showed that changes in the other blood factors, may be an effective tool to show IFD lung in patients with underlying conditions should be considered, even though more studies to accurately assess the quantities of other blood components and the amount of sediment blood cells for many of the abnormalities is necessary.